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Darrell Kretchmar _Genetic Problem Set

Darrell Kretchmar _Genetic Problem Set

Q Genetics Problem Set 1. A cross between a short-tailed mouse and a long-tailed mouse yields all short-tailed mice. Crosses among the F1 yield an F2 of 48 short-tailed mice and 22 long-tailed mice. Propose a model (e.g., diagram the cross) to explain these results. 2. A hypothetical human trait is controlled by a single gene locus. Four alleles have been identified: a, b, c, and d. Alleles a, b, and c are all codominant; allele d is recessive to all other alleles. a. How many phenotypes are possible? b. How many genotypes are possible?3. What is the chance that a man with type AB blood and a woman with type A blood whose mother is type O can produce a child that is: 4. Hemophilia is an X-linked recessive disorder. A normal woman whose father was hemophiliac marries a normal man. They have a hemophilic son. The man claims his wife has been unfaithful. If you were the judge, how would you rule and why?

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Ans:Let the gene for short tail is S and long tail is s.All the offspring’s were short tail in F1 indicated that the gene for short tail is dominant on long tail.Ans: Possible phenotypes are a, hybrid ab, hybrid ac,b, hybrid bc ,c, dAns: Possible genotypes are aa, ab, ac, ad, bb, bc, bd,ba, cc, cd, ca, cb, dd